STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTCH2Protein patched homolog 2 isoform 1. (1203 aa)    
Predicted Functional Partners:
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.996
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.993
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.993
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.991
CDON
Cell adhesion associated, oncogene regulated.
    
 0.988
GAS1
Growth arrest specific 1.
     
 0.985
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.970
SMURF1
E3 ubiquitin-protein ligase.
    
 0.965
SMURF2
E3 ubiquitin-protein ligase.
    
 0.965
PTCH1
Protein patched homolog 1 isoform L.
  
  
0.920
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.