| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHRNB2 | IL1B | ENSCJAP00000017473 | ENSCJAP00000030094 | Neuronal acetylcholine receptor subunit beta-2. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.644 |
| CHRNB2 | NMUR2 | ENSCJAP00000017473 | ENSCJAP00000008622 | Neuronal acetylcholine receptor subunit beta-2. | Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.645 |
| CHRNB2 | PPT1 | ENSCJAP00000017473 | ENSCJAP00000044765 | Neuronal acetylcholine receptor subunit beta-2. | Palmitoyl-protein thioesterase 1. | 0.645 |
| GNG2 | NMS | ENSCJAP00000061696 | ENSCJAP00000018679 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Neuromedin S. | 0.635 |
| GNG2 | NMU | ENSCJAP00000061696 | ENSCJAP00000074173 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | NMU domain-containing protein. | 0.665 |
| GNG2 | NMUR1 | ENSCJAP00000061696 | ENSCJAP00000024999 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.635 |
| GNG2 | NMUR2 | ENSCJAP00000061696 | ENSCJAP00000008622 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.635 |
| GNG2 | POMC | ENSCJAP00000061696 | ENSCJAP00000059725 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Pro-opiomelanocortin preproprotein. | 0.773 |
| IL1B | CHRNB2 | ENSCJAP00000030094 | ENSCJAP00000017473 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Neuronal acetylcholine receptor subunit beta-2. | 0.644 |
| IL1B | NMUR1 | ENSCJAP00000030094 | ENSCJAP00000024999 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.504 |
| IL1B | NMUR2 | ENSCJAP00000030094 | ENSCJAP00000008622 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.644 |
| IL1B | PPT1 | ENSCJAP00000030094 | ENSCJAP00000044765 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Palmitoyl-protein thioesterase 1. | 0.670 |
| NMS | GNG2 | ENSCJAP00000018679 | ENSCJAP00000061696 | Neuromedin S. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.635 |
| NMS | NMU | ENSCJAP00000018679 | ENSCJAP00000074173 | Neuromedin S. | NMU domain-containing protein. | 0.823 |
| NMS | NMUR1 | ENSCJAP00000018679 | ENSCJAP00000024999 | Neuromedin S. | Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.960 |
| NMS | NMUR2 | ENSCJAP00000018679 | ENSCJAP00000008622 | Neuromedin S. | Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.993 |
| NMS | NPS | ENSCJAP00000018679 | ENSCJAP00000076845 | Neuromedin S. | Uncharacterized protein. | 0.609 |
| NMS | NTS | ENSCJAP00000018679 | ENSCJAP00000055110 | Neuromedin S. | Neurotensin/neuromedin N preproprotein. | 0.464 |
| NMS | POMC | ENSCJAP00000018679 | ENSCJAP00000059725 | Neuromedin S. | Pro-opiomelanocortin preproprotein. | 0.588 |
| NMU | GNG2 | ENSCJAP00000074173 | ENSCJAP00000061696 | NMU domain-containing protein. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.665 |