STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.821
CEP55
Centrosomal protein 55.
   
  
 0.693
CDC20
Cell division cycle 20.
   
 
 0.674
NDC80
NDC80 kinetochore complex component.
   
 
 0.631
CKAP2L
Cytoskeleton associated protein 2 like.
   
    0.629
CDC20B
Cell division cycle 20B.
   
 
 0.629
HOXD13
Homeobox protein Hox-D13.
      
 0.525
BUB1B
Uncharacterized protein.
   
 
 0.517
PLK4
Serine/threonine-protein kinase PLK4 isoform 1.
   
 
  0.515
ZWILCH
Zwilch kinetochore protein.
   
  
 0.513
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.