STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHEXPhosphate regulating endopeptidase homolog X-linked. (749 aa)    
Predicted Functional Partners:
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 
 0.850
MEPE
Matrix extracellular phosphoglycoprotein.
   
 
 0.809
PHOSPHO1
Phosphoethanolamine/phosphocholine phosphatase.
      
 0.778
ENSCJAP00000075867
Sclerostin.
    
 
 0.719
DMP1
Dentin matrix acidic phosphoprotein 1.
      
 0.711
CLCN7
Chloride channel protein.
      
 0.646
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.646
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
      
 0.644
PTH
Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.
      
 0.640
LRP5
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
   
  
 0.638
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.