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CAV2 protein (Callithrix jacchus) - STRING interaction network
"CAV2" - Caveolin-2 in Callithrix jacchus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)    
Predicted Functional Partners:
CAV1
Caveolin-1; Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G- protein alpha subunits and can functionally regulate their activity. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wn [...] (178 aa)
     
0.961
SRC
Tyrosine-protein kinase; SRC proto-oncogene, non-receptor tyrosine kinase (542 aa)
     
  0.906
EGFR
Receptor protein-tyrosine kinase; Epidermal growth factor receptor (1210 aa)
     
  0.863
FYN
FYN proto-oncogene, Src family tyrosine kinase (537 aa)
     
  0.853
NOS3
Nitric oxide synthase; Produces nitric oxide (NO) (1197 aa)
       
  0.851
CALM1
Calmodulin 1 (phosphorylase kinase, delta) (149 aa)
       
  0.839
CAV3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (148 aa)
     
0.829
ENSCJAG00000009940
Uncharacterized protein (222 aa)
       
  0.810
HSP90AA1
Heat shock protein 90 alpha family class A member 1 (606 aa)
       
  0.808
HSP90B1
Heat shock protein 90kDa beta (Grp94), member 1 (804 aa)
       
  0.808
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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