NKX6-1 protein (Callithrix jacchus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

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Experiments

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[Homology]

Score

NKX6-1

NK6 homeobox 1. (366 aa)

Predicted Functional Partners:

IRX2

0.557

PDX1

0.505

PTF1A

0.501

HNF1B

0.501

POU3F3

0.467

FOXK1

0.459

FOXA2

0.453

LHX4

0.453

UCN3

0.441

INS

0.435

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXA2	HNF1B	ENSCJAP00000010628	ENSCJAP00000027992	Forkhead box A2.	HNF1 homeobox B.	0.477
FOXA2	INS	ENSCJAP00000010628	ENSCJAP00000034117	Forkhead box A2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.449
FOXA2	NKX6-1	ENSCJAP00000010628	ENSCJAP00000009744	Forkhead box A2.	NK6 homeobox 1.	0.453
FOXA2	PDX1	ENSCJAP00000010628	ENSCJAP00000074029	Forkhead box A2.	Homeobox domain-containing protein.	0.749
FOXK1	NKX6-1	ENSCJAP00000034705	ENSCJAP00000009744	Forkhead box K1.	NK6 homeobox 1.	0.459
FOXK1	POU3F3	ENSCJAP00000034705	ENSCJAP00000054945	Forkhead box K1.	POU domain protein.	0.490
HNF1B	FOXA2	ENSCJAP00000027992	ENSCJAP00000010628	HNF1 homeobox B.	Forkhead box A2.	0.477
HNF1B	NKX6-1	ENSCJAP00000027992	ENSCJAP00000009744	HNF1 homeobox B.	NK6 homeobox 1.	0.501
HNF1B	PDX1	ENSCJAP00000027992	ENSCJAP00000074029	HNF1 homeobox B.	Homeobox domain-containing protein.	0.600
INS	FOXA2	ENSCJAP00000034117	ENSCJAP00000010628	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Forkhead box A2.	0.449
INS	NKX6-1	ENSCJAP00000034117	ENSCJAP00000009744	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NK6 homeobox 1.	0.435
INS	PDX1	ENSCJAP00000034117	ENSCJAP00000074029	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Homeobox domain-containing protein.	0.823
INS	PTF1A	ENSCJAP00000034117	ENSCJAP00000014571	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Pancreas associated transcription factor 1a.	0.637
INS	UCN3	ENSCJAP00000034117	ENSCJAP00000000901	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Urocortin-3 preproprotein.	0.411
IRX2	NKX6-1	ENSCJAP00000068542	ENSCJAP00000009744	Iroquois homeobox 2.	NK6 homeobox 1.	0.557
LHX4	NKX6-1	ENSCJAP00000014754	ENSCJAP00000009744	LIM homeobox 4.	NK6 homeobox 1.	0.453
LHX4	POU3F3	ENSCJAP00000014754	ENSCJAP00000054945	LIM homeobox 4.	POU domain protein.	0.469
NKX6-1	FOXA2	ENSCJAP00000009744	ENSCJAP00000010628	NK6 homeobox 1.	Forkhead box A2.	0.453
NKX6-1	FOXK1	ENSCJAP00000009744	ENSCJAP00000034705	NK6 homeobox 1.	Forkhead box K1.	0.459
NKX6-1	HNF1B	ENSCJAP00000009744	ENSCJAP00000027992	NK6 homeobox 1.	HNF1 homeobox B.	0.501