STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFIL3Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa)    
Predicted Functional Partners:
BHLHE41
Class E basic helix-loop-helix protein 41.
    
 0.795
PER2
Period circadian regulator 2.
   
 0.751
NR1D2
Nuclear receptor subfamily 1 group D member 2 isoform 1.
   
 0.720
NPAS2
Neuronal PAS domain-containing protein 2.
    
 0.678
HLF
Hepatic leukemia factor.
    
 
0.663
ARNTL
Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform a.
   
 0.661
PER3
PAS domain-containing protein.
   
 0.658
CRY1
Cryptochrome circadian regulator 1.
   
  
 0.599
LOC100401281
Uncharacterized protein.
   
 0.589
COX5A
Uncharacterized protein.
   
 0.589
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.