| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APAF1 | BIRC2 | ENSCJAP00000004308 | ENSCJAP00000006902 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Baculoviral IAP repeat-containing protein 2 isoform 1. | 0.710 |
| APAF1 | CASP3 | ENSCJAP00000004308 | ENSCJAP00000010532 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 3; Belongs to the peptidase C14A family. | 0.996 |
| APAF1 | CASP9 | ENSCJAP00000004308 | ENSCJAP00000016114 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 9; Belongs to the peptidase C14A family. | 0.999 |
| APAF1 | LOC100401718 | ENSCJAP00000004308 | ENSCJAP00000061447 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.999 |
| APAF1 | LOC100406761 | ENSCJAP00000004308 | ENSCJAP00000058896 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.999 |
| APAF1 | LOC100413276 | ENSCJAP00000004308 | ENSCJAP00000056047 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.999 |
| APAF1 | LOC108593648 | ENSCJAP00000004308 | ENSCJAP00000063186 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.999 |
| APAF1 | PARP1 | ENSCJAP00000004308 | ENSCJAP00000072405 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Poly [ADP-ribose] polymerase. | 0.471 |
| APAF1 | XIAP | ENSCJAP00000004308 | ENSCJAP00000038195 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Baculoviral IAP repeat-containing 4 (Predicted). | 0.918 |
| BIRC2 | APAF1 | ENSCJAP00000006902 | ENSCJAP00000004308 | Baculoviral IAP repeat-containing protein 2 isoform 1. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.710 |
| BIRC2 | CASP3 | ENSCJAP00000006902 | ENSCJAP00000010532 | Baculoviral IAP repeat-containing protein 2 isoform 1. | Caspase 3; Belongs to the peptidase C14A family. | 0.986 |
| BIRC2 | CASP9 | ENSCJAP00000006902 | ENSCJAP00000016114 | Baculoviral IAP repeat-containing protein 2 isoform 1. | Caspase 9; Belongs to the peptidase C14A family. | 0.992 |
| BIRC2 | XIAP | ENSCJAP00000006902 | ENSCJAP00000038195 | Baculoviral IAP repeat-containing protein 2 isoform 1. | Baculoviral IAP repeat-containing 4 (Predicted). | 0.990 |
| CASP3 | APAF1 | ENSCJAP00000010532 | ENSCJAP00000004308 | Caspase 3; Belongs to the peptidase C14A family. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.996 |
| CASP3 | BIRC2 | ENSCJAP00000010532 | ENSCJAP00000006902 | Caspase 3; Belongs to the peptidase C14A family. | Baculoviral IAP repeat-containing protein 2 isoform 1. | 0.986 |
| CASP3 | CASP9 | ENSCJAP00000010532 | ENSCJAP00000016114 | Caspase 3; Belongs to the peptidase C14A family. | Caspase 9; Belongs to the peptidase C14A family. | 0.993 |
| CASP3 | DFFA | ENSCJAP00000010532 | ENSCJAP00000009270 | Caspase 3; Belongs to the peptidase C14A family. | DNAation factor subunit alpha isoform 1. | 0.987 |
| CASP3 | LOC100401718 | ENSCJAP00000010532 | ENSCJAP00000061447 | Caspase 3; Belongs to the peptidase C14A family. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.994 |
| CASP3 | LOC100406761 | ENSCJAP00000010532 | ENSCJAP00000058896 | Caspase 3; Belongs to the peptidase C14A family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.994 |
| CASP3 | LOC100413276 | ENSCJAP00000010532 | ENSCJAP00000056047 | Caspase 3; Belongs to the peptidase C14A family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.994 |