STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFIT1Interferon-induced protein with tetratricopeptide repeats 1 isoform 1. (478 aa)    
Predicted Functional Partners:
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 0.957
EIF3E
Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
    
 0.920
EIF2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3.
   
  0.910
EIF2AK1
Eukaryotic translation initiation factor 2 alpha kinase 1.
  
 
 0.903
EIF2AK4
Eukaryotic translation initiation factor 2-alpha kinase 4.
  
 
 0.902
ISG15
ISG15 ubiquitin like modifier.
   
 0.890
MX2
MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.869
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.841
IFIT3
Interferon induced protein with tetratricopeptide repeats 3.
  
 
0.808
RSAD2
Radical S-adenosyl methionine domain-containing protein 2.
   
 
 0.777
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.