STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP3Poly [ADP-ribose] polymerase. (563 aa)    
Predicted Functional Partners:
PARG
Poly(ADP-ribose) glycohydrolase.
    
 0.959
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.923
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.923
CASP7
Caspase 7; Belongs to the peptidase C14A family.
    
 0.923
GZMB
Granzyme B; Belongs to the peptidase S1 family.
   
  0.903
APLF
Aprataxin and PNKP like factor.
    
 
 0.855
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.785
PARP6
Poly [ADP-ribose] polymerase.
      
 0.781
LOC100399369
UPF0609 protein C4orf27.
    
 
 0.760
XRCC1
X-ray repair cross complementing 1.
    
 
 0.758
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.