node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BTLA | CD40LG | ENSCJAP00000059299 | ENSCJAP00000056697 | B and T lymphocyte associated. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.491 |
BTLA | TNFRSF11B | ENSCJAP00000059299 | ENSCJAP00000010665 | B and T lymphocyte associated. | TNF receptor superfamily member 11b. | 0.657 |
BTLA | TNFSF14 | ENSCJAP00000059299 | ENSCJAP00000078044 | B and T lymphocyte associated. | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. | 0.574 |
CD40LG | BTLA | ENSCJAP00000056697 | ENSCJAP00000059299 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | B and T lymphocyte associated. | 0.491 |
CD40LG | LTA | ENSCJAP00000056697 | ENSCJAP00000064936 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | 0.671 |
CD40LG | TNFRSF11A | ENSCJAP00000056697 | ENSCJAP00000006048 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF receptor superfamily member 11a. | 0.572 |
CD40LG | TNFRSF11B | ENSCJAP00000056697 | ENSCJAP00000010665 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF receptor superfamily member 11b. | 0.685 |
CD40LG | TNFSF11 | ENSCJAP00000056697 | ENSCJAP00000032488 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Tumor necrosis factor ligand superfamily member. | 0.600 |
CD40LG | TNFSF14 | ENSCJAP00000056697 | ENSCJAP00000078044 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. | 0.579 |
FOSL1 | TNFRSF11B | ENSCJAP00000003194 | ENSCJAP00000010665 | FOS like 1, AP-1 transcription factor subunit. | TNF receptor superfamily member 11b. | 0.546 |
LTA | CD40LG | ENSCJAP00000064936 | ENSCJAP00000056697 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.671 |
LTA | TNFRSF11A | ENSCJAP00000064936 | ENSCJAP00000006048 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | TNF receptor superfamily member 11a. | 0.408 |
LTA | TNFRSF11B | ENSCJAP00000064936 | ENSCJAP00000010665 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | TNF receptor superfamily member 11b. | 0.623 |
LTA | TNFSF11 | ENSCJAP00000064936 | ENSCJAP00000032488 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | Tumor necrosis factor ligand superfamily member. | 0.607 |
LTA | TNFSF14 | ENSCJAP00000064936 | ENSCJAP00000078044 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. | 0.486 |
OR10J1 | TNFRSF11B | ENSCJAP00000040709 | ENSCJAP00000010665 | Olfactory receptor. | TNF receptor superfamily member 11b. | 0.610 |
TNFRSF11A | CD40LG | ENSCJAP00000006048 | ENSCJAP00000056697 | TNF receptor superfamily member 11a. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.572 |
TNFRSF11A | LTA | ENSCJAP00000006048 | ENSCJAP00000064936 | TNF receptor superfamily member 11a. | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | 0.408 |
TNFRSF11A | TNFRSF11B | ENSCJAP00000006048 | ENSCJAP00000010665 | TNF receptor superfamily member 11a. | TNF receptor superfamily member 11b. | 0.581 |
TNFRSF11A | TNFSF11 | ENSCJAP00000006048 | ENSCJAP00000032488 | TNF receptor superfamily member 11a. | Tumor necrosis factor ligand superfamily member. | 0.998 |