Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD44 | CDH1 | ENSCJAP00000043230 | ENSCJAP00000028627 | CD44 molecule (Indian blood group). | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. | 0.568 |
| CD44 | MET | ENSCJAP00000043230 | ENSCJAP00000009442 | CD44 molecule (Indian blood group). | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.694 |
| CD44 | S100A8 | ENSCJAP00000043230 | ENSCJAP00000010722 | CD44 molecule (Indian blood group). | Protein S100; Belongs to the S-100 family. | 0.590 |
| CDH1 | CD44 | ENSCJAP00000028627 | ENSCJAP00000043230 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. | CD44 molecule (Indian blood group). | 0.568 |
| CDH1 | MET | ENSCJAP00000028627 | ENSCJAP00000009442 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.644 |
| CDH1 | S100A8 | ENSCJAP00000028627 | ENSCJAP00000010722 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. | Protein S100; Belongs to the S-100 family. | 0.594 |
| CDH1 | TJP1 | ENSCJAP00000028627 | ENSCJAP00000032151 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. | Tight junction protein 1; Belongs to the MAGUK family. | 0.697 |
| GRB2 | MET | ENSCJAP00000067776 | ENSCJAP00000009442 | Growth factor receptor-bound protein 2 isoform 1. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.995 |
| GRB2 | PTPN11 | ENSCJAP00000067776 | ENSCJAP00000022937 | Growth factor receptor-bound protein 2 isoform 1. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.999 |
| GRB2 | S100A8 | ENSCJAP00000067776 | ENSCJAP00000010722 | Growth factor receptor-bound protein 2 isoform 1. | Protein S100; Belongs to the S-100 family. | 0.646 |
| ITIH4 | S100A12 | ENSCJAP00000045186 | ENSCJAP00000010723 | Inter-alpha-trypsin inhibitor heavy chain 4. | S100 calcium binding protein A12; Belongs to the S-100 family. | 0.482 |
| ITIH4 | S100A8 | ENSCJAP00000045186 | ENSCJAP00000010722 | Inter-alpha-trypsin inhibitor heavy chain 4. | Protein S100; Belongs to the S-100 family. | 0.603 |
| MET | CD44 | ENSCJAP00000009442 | ENSCJAP00000043230 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | CD44 molecule (Indian blood group). | 0.694 |
| MET | CDH1 | ENSCJAP00000009442 | ENSCJAP00000028627 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. | 0.644 |
| MET | GRB2 | ENSCJAP00000009442 | ENSCJAP00000067776 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Growth factor receptor-bound protein 2 isoform 1. | 0.995 |
| MET | PTPN11 | ENSCJAP00000009442 | ENSCJAP00000022937 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.780 |
| MET | S100A8 | ENSCJAP00000009442 | ENSCJAP00000010722 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Protein S100; Belongs to the S-100 family. | 0.619 |
| PTPN11 | GRB2 | ENSCJAP00000022937 | ENSCJAP00000067776 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | Growth factor receptor-bound protein 2 isoform 1. | 0.999 |
| PTPN11 | MET | ENSCJAP00000022937 | ENSCJAP00000009442 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.780 |
| PTPN11 | S100A8 | ENSCJAP00000022937 | ENSCJAP00000010722 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | Protein S100; Belongs to the S-100 family. | 0.668 |
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