STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLR9TIR domain-containing protein. (1032 aa)    
Predicted Functional Partners:
TLR7
Toll like receptor 7; Belongs to the Toll-like receptor family.
  
 
0.980
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.976
TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein isoform a.
   
 0.961
TICAM2
TIR domain-containing adapter molecule 2.
   
 0.950
TICAM1
TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.
   
 0.938
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
     
0.934
LY96
Lymphocyte antigen 96.
   
 0.804
UNC93B1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.801
TLR8
Toll like receptor 8; Belongs to the Toll-like receptor family.
    
0.728
TWF2
Twinfilin actin binding protein 2.
 
 
  
 0.728
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (18%) [HD]