Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GMNNGeminin DNA replication inhibitor. (209 aa)    
Predicted Functional Partners:
CDT1
Chromatin licensing and DNA replication factor 1.
   
 0.998
MCM6
DNA helicase; Belongs to the MCM family.
   
 0.963
ORC6
Origin recognition complex subunit 6.
   
 
 0.916
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.910
ORC4
Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.
     
 0.906
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 
 0.888
CDC20
Cell division cycle 20.
   
 0.885
MCM8
MCM domain-containing protein; Belongs to the MCM family.
   
 0.877
MCM5
DNA helicase; Belongs to the MCM family.
   
 
 0.875
CCNA2
Cyclin-A2; Belongs to the cyclin family.
   
 
 0.868
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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