STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B1SH2B adaptor protein 1. (830 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2 isoform 1.
    
 0.965
NTRK1
Tyrosine-protein kinase receptor.
    
 0.939
NTRK3
Tyrosine-protein kinase receptor.
    
 0.930
NTRK2
Tyrosine-protein kinase receptor.
    
 0.928
SH2B3
SH2B adaptor protein 3.
    
0.906
JAK2
Tyrosine-protein kinase.
   
 0.830
INSR
Tyrosine-protein kinase receptor.
    
 0.736
REPIN1
Replication initiator 1 isoform 3.
      
 0.725
GJB4
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.725
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.710
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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