| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GRB2 | IGF1 | ENSCJAP00000067776 | ENSCJAP00000056775 | Growth factor receptor-bound protein 2 isoform 1. | Insulin like growth factor 1. | 0.634 |
| GRB2 | INS | ENSCJAP00000067776 | ENSCJAP00000034117 | Growth factor receptor-bound protein 2 isoform 1. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.741 |
| GRB2 | INSR | ENSCJAP00000067776 | ENSCJAP00000053402 | Growth factor receptor-bound protein 2 isoform 1. | Tyrosine-protein kinase receptor. | 0.965 |
| GRB2 | INSRR | ENSCJAP00000067776 | ENSCJAP00000011677 | Growth factor receptor-bound protein 2 isoform 1. | Tyrosine-protein kinase receptor. | 0.952 |
| GRB2 | PIK3R1 | ENSCJAP00000067776 | ENSCJAP00000029505 | Growth factor receptor-bound protein 2 isoform 1. | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1. | 0.966 |
| GRB2 | PIK3R2 | ENSCJAP00000067776 | ENSCJAP00000025887 | Growth factor receptor-bound protein 2 isoform 1. | Phosphatidylinositol 3-kinase regulatory subunit beta. | 0.830 |
| GRB2 | PIK3R3 | ENSCJAP00000067776 | ENSCJAP00000039097 | Growth factor receptor-bound protein 2 isoform 1. | Phosphatidylinositol 3-kinase regulatory subunit gamma. | 0.830 |
| GRB2 | PTPN1 | ENSCJAP00000067776 | ENSCJAP00000000909 | Growth factor receptor-bound protein 2 isoform 1. | Tyrosine-protein phosphatase non-receptor type. | 0.637 |
| GRB2 | SOS1 | ENSCJAP00000067776 | ENSCJAP00000027786 | Growth factor receptor-bound protein 2 isoform 1. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.999 |
| GRB2 | SOS2 | ENSCJAP00000067776 | ENSCJAP00000049426 | Growth factor receptor-bound protein 2 isoform 1. | SOS Ras/Rho guanine nucleotide exchange factor 2. | 0.999 |
| IGF1 | GRB2 | ENSCJAP00000056775 | ENSCJAP00000067776 | Insulin like growth factor 1. | Growth factor receptor-bound protein 2 isoform 1. | 0.634 |
| IGF1 | INS | ENSCJAP00000056775 | ENSCJAP00000034117 | Insulin like growth factor 1. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.993 |
| IGF1 | INSR | ENSCJAP00000056775 | ENSCJAP00000053402 | Insulin like growth factor 1. | Tyrosine-protein kinase receptor. | 0.997 |
| IGF1 | INSRR | ENSCJAP00000056775 | ENSCJAP00000011677 | Insulin like growth factor 1. | Tyrosine-protein kinase receptor. | 0.947 |
| IGF1 | SOS1 | ENSCJAP00000056775 | ENSCJAP00000027786 | Insulin like growth factor 1. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.482 |
| INS | GRB2 | ENSCJAP00000034117 | ENSCJAP00000067776 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Growth factor receptor-bound protein 2 isoform 1. | 0.741 |
| INS | IGF1 | ENSCJAP00000034117 | ENSCJAP00000056775 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Insulin like growth factor 1. | 0.993 |
| INS | INSR | ENSCJAP00000034117 | ENSCJAP00000053402 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Tyrosine-protein kinase receptor. | 0.994 |
| INS | INSRR | ENSCJAP00000034117 | ENSCJAP00000011677 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Tyrosine-protein kinase receptor. | 0.988 |
| INS | PIK3R2 | ENSCJAP00000034117 | ENSCJAP00000025887 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Phosphatidylinositol 3-kinase regulatory subunit beta. | 0.462 |