Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HERC5HECT and RLD domain containing E3 ubiquitin protein ligase 5. (1165 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 0.989
RSAD2
Radical S-adenosyl methionine domain-containing protein 2.
   
 
 0.931
IFIT2
Interferon induced protein with tetratricopeptide repeats 2.
   
 
 0.905
IFIT3
Interferon induced protein with tetratricopeptide repeats 3.
   
 
 0.903
OASL
2'-5'-oligoadenylate synthetase like.
   
 0.874
IFIH1
Interferon induced with helicase C domain 1.
   
 
 0.850
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 
 0.849
UBE2L6
Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.841
UBA7
Ubiquitin-like modifier-activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
 0.840
DDX58
Putative ATP-dependent RNA helicase DDX58.
   
 
 0.830
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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