NR6A1 protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NR6A1

Nuclear receptor subfamily 6 group A member 1. (480 aa)

Predicted Functional Partners:

NCOR1

0.714

NCOR2

0.687

BOLL

0.623

MUL1

0.622

MED1

0.616

UIMC1

0.593

ATP6V0A2

0.542

FAM9B

0.524

PIWIL1

0.521

DAZL

0.520

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0A2	NR6A1	ENSCJAP00000038113	ENSCJAP00000012293	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Nuclear receptor subfamily 6 group A member 1.	0.542
BOLL	FAM9B	ENSCJAP00000007438	ENSCJAP00000001533	Boule homolog, RNA binding protein.	Family with sequence similarity 9 member B.	0.546
BOLL	NR6A1	ENSCJAP00000007438	ENSCJAP00000012293	Boule homolog, RNA binding protein.	Nuclear receptor subfamily 6 group A member 1.	0.623
BOLL	PIWIL1	ENSCJAP00000007438	ENSCJAP00000020124	Boule homolog, RNA binding protein.	Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.	0.620
DAZL	FAM9B	ENSCJAP00000006526	ENSCJAP00000001533	Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity).	Family with sequence similarity 9 member B.	0.496
DAZL	NR6A1	ENSCJAP00000006526	ENSCJAP00000012293	Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity).	Nuclear receptor subfamily 6 group A member 1.	0.520
DAZL	PIWIL1	ENSCJAP00000006526	ENSCJAP00000020124	Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity).	Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.	0.750
FAM9B	BOLL	ENSCJAP00000001533	ENSCJAP00000007438	Family with sequence similarity 9 member B.	Boule homolog, RNA binding protein.	0.546
FAM9B	DAZL	ENSCJAP00000001533	ENSCJAP00000006526	Family with sequence similarity 9 member B.	Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity).	0.496
FAM9B	NR6A1	ENSCJAP00000001533	ENSCJAP00000012293	Family with sequence similarity 9 member B.	Nuclear receptor subfamily 6 group A member 1.	0.524
MED1	NCOR1	ENSCJAP00000015874	ENSCJAP00000022329	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 1.	0.606
MED1	NCOR2	ENSCJAP00000015874	ENSCJAP00000049515	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 2.	0.663
MED1	NR6A1	ENSCJAP00000015874	ENSCJAP00000012293	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 6 group A member 1.	0.616
MUL1	NR6A1	ENSCJAP00000057740	ENSCJAP00000012293	Mitochondrial E3 ubiquitin protein ligase 1.	Nuclear receptor subfamily 6 group A member 1.	0.622
NCOR1	MED1	ENSCJAP00000022329	ENSCJAP00000015874	Nuclear receptor corepressor 1.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.606
NCOR1	NCOR2	ENSCJAP00000022329	ENSCJAP00000049515	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 2.	0.932
NCOR1	NR6A1	ENSCJAP00000022329	ENSCJAP00000012293	Nuclear receptor corepressor 1.	Nuclear receptor subfamily 6 group A member 1.	0.714
NCOR2	MED1	ENSCJAP00000049515	ENSCJAP00000015874	Nuclear receptor corepressor 2.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.663
NCOR2	NCOR1	ENSCJAP00000049515	ENSCJAP00000022329	Nuclear receptor corepressor 2.	Nuclear receptor corepressor 1.	0.932
NCOR2	NR6A1	ENSCJAP00000049515	ENSCJAP00000012293	Nuclear receptor corepressor 2.	Nuclear receptor subfamily 6 group A member 1.	0.687