Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LAX1Lymphocyte transmembrane adaptor 1. (428 aa)    
Predicted Functional Partners:
GRB7
Growth factor receptor bound protein 7.
    
   0.809
GAPT
GRB2 binding adaptor protein, transmembrane.
      
 0.665
CLNK
Cytokine dependent hematopoietic cell linker.
      
 0.610
CD320
CD320 molecule.
      
 0.548
SLCO3A1
Solute carrier organic anion transporter family member.
      
 0.548
GRB14
Growth factor receptor bound protein 14.
    
   0.532
GRB10
Growth factor receptor bound protein 10.
    
   0.532
DERL3
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
  
 0.517
LOC100402350
Uncharacterized protein.
      
 0.508
CD27
CD27 molecule.
   
  
 0.498
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (12%) [HD]