Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DPYSDihydropyrimidinase. (519 aa)    
Predicted Functional Partners:
DPYD
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.
  
 0.988
UPB1
Beta-ureidopropionase 1.
 
 
 0.977
DPYSL3
Dihydropyrimidinase like 3.
   
  0.927
DPYSL5
Dihydropyrimidinase-related protein 5.
    
 0.891
UMPS
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.
  
  
 0.883
CRMP1
Collapsin response mediator protein 1.
   
  0.856
DPYSL2
Dihydropyrimidinase-related protein 2 isoform 1.
    
   0.846
DPYSL4
Dihydropyrimidinase-related protein 4.
   
  0.818
DHODH
Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.749
HPDL
4-hydroxyphenylpyruvate dioxygenase.
  
  
 0.707
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.