Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F10Coagulation factor X. (494 aa)    
Predicted Functional Partners:
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.982
TFPI
Tissue factor pathway inhibitor.
    
 0.965
F7
Coagulation factor VII.
   
 0.960
F5
Coagulation factor V; Belongs to the multicopper oxidase family.
   
 0.958
GGCX
Gamma-glutamyl carboxylase.
    
 0.955
F3
Coagulation factor III, tissue factor.
    
 0.950
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
   
 0.935
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
   
 0.927
ASPH
Aspartate beta-hydroxylase.
    
 0.827
F9
Coagulation factor IX.
   
 0.812
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (12%) [HD]