Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F12Coagulation factor XII. (612 aa)    
Predicted Functional Partners:
KLKB1
Kallikrein B1; Belongs to the peptidase S1 family.
  
0.943
SERPING1
Serpin family G member 1; Belongs to the serpin family.
   
 0.942
KNG1
Kininogen 1.
   
 0.921
IGFALS
Insulin like growth factor binding protein acid labile subunit.
   
 0.874
C6
Complement C6.
   
 
 0.849
C8B
Complement C8 beta chain.
   
 
 0.838
C7
Complement C7.
   
 
 0.822
C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial.
    
 0.816
C8G
Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family.
   
 0.812
SPINT1
Serine peptidase inhibitor, Kunitz type 1.
    
 0.807
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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