STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINB3Serine proteinase inhibitor, clade B, member 4 (Predicted); Belongs to the serpin family. (387 aa)    
Predicted Functional Partners:
CTSG
Cathepsin G; Belongs to the peptidase S1 family.
    
 0.941
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.580
CTSS
Cathepsin S isoform 1 preproprotein; Belongs to the peptidase C1 family.
    
 0.559
CTSL
Uncharacterized protein; Belongs to the peptidase C1 family.
   
 0.534
ENSCJAP00000073690
Uncharacterized protein; Belongs to the peptidase C1 family.
   
 0.534
CTSV
Cathepsin V; Belongs to the peptidase C1 family.
   
 0.517
CTSK
Cathepsin K preproprotein; Belongs to the peptidase C1 family.
    
 0.511
CCL27
C-C motif chemokine ligand 27.
     
 0.497
CPA3
Carboxypeptidase A3.
     
 0.495
ARPC2
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
 
      0.493
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.