MCOLN2 protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MCOLN2

Mucolipin 2. (574 aa)

Predicted Functional Partners:

MCOLN3

0.980

MCOLN1

0.973

PDF

0.583

P2RY6

0.568

API5

0.553

VSIG10

0.531

TRPA1

0.473

ADAR

0.473

ENSCJAP00000074997

0.450

DNAJC14

0.444

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAR	MCOLN2	ENSCJAP00000017279	ENSCJAP00000012690	Adenosine deaminase RNA specific.	Mucolipin 2.	0.473
API5	MCOLN2	ENSCJAP00000062021	ENSCJAP00000012690	Uncharacterized protein.	Mucolipin 2.	0.553
API5	VSIG10	ENSCJAP00000062021	ENSCJAP00000017089	Uncharacterized protein.	V-set and immunoglobulin domain containing 10.	0.579
DNAJC14	MCOLN2	ENSCJAP00000014514	ENSCJAP00000012690	J domain-containing protein.	Mucolipin 2.	0.444
ENSCJAP00000074997	MCOLN1	ENSCJAP00000074997	ENSCJAP00000015617	LSDAT_euk domain-containing protein.	Mucolipin 1.	0.500
ENSCJAP00000074997	MCOLN2	ENSCJAP00000074997	ENSCJAP00000012690	LSDAT_euk domain-containing protein.	Mucolipin 2.	0.450
ENSCJAP00000074997	MCOLN3	ENSCJAP00000074997	ENSCJAP00000012762	LSDAT_euk domain-containing protein.	Mucolipin-3; Nonselective ligand-gated cation channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation channel with inwardly rectifying activity (By similarity). Mediates release of Ca(2+) from endosomes to the cytoplasm, contributes to endosomal acidification and is involved in the regulation of membrane trafficking and fusion in the endosomal pathway (By similarity). Does not seem to act as mechanosensory transduction channel in inner ear sensory hair cells. Proposed to play a critical role at the cochlear stereocilia ankle-lin [...]	0.452
ENSCJAP00000074997	TRPA1	ENSCJAP00000074997	ENSCJAP00000014378	LSDAT_euk domain-containing protein.	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.539
MCOLN1	ENSCJAP00000074997	ENSCJAP00000015617	ENSCJAP00000074997	Mucolipin 1.	LSDAT_euk domain-containing protein.	0.500
MCOLN1	MCOLN2	ENSCJAP00000015617	ENSCJAP00000012690	Mucolipin 1.	Mucolipin 2.	0.973
MCOLN1	MCOLN3	ENSCJAP00000015617	ENSCJAP00000012762	Mucolipin 1.	Mucolipin-3; Nonselective ligand-gated cation channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation channel with inwardly rectifying activity (By similarity). Mediates release of Ca(2+) from endosomes to the cytoplasm, contributes to endosomal acidification and is involved in the regulation of membrane trafficking and fusion in the endosomal pathway (By similarity). Does not seem to act as mechanosensory transduction channel in inner ear sensory hair cells. Proposed to play a critical role at the cochlear stereocilia ankle-lin [...]	0.970
MCOLN1	TRPA1	ENSCJAP00000015617	ENSCJAP00000014378	Mucolipin 1.	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.473
MCOLN2	ADAR	ENSCJAP00000012690	ENSCJAP00000017279	Mucolipin 2.	Adenosine deaminase RNA specific.	0.473
MCOLN2	API5	ENSCJAP00000012690	ENSCJAP00000062021	Mucolipin 2.	Uncharacterized protein.	0.553
MCOLN2	DNAJC14	ENSCJAP00000012690	ENSCJAP00000014514	Mucolipin 2.	J domain-containing protein.	0.444
MCOLN2	ENSCJAP00000074997	ENSCJAP00000012690	ENSCJAP00000074997	Mucolipin 2.	LSDAT_euk domain-containing protein.	0.450
MCOLN2	MCOLN1	ENSCJAP00000012690	ENSCJAP00000015617	Mucolipin 2.	Mucolipin 1.	0.973
MCOLN2	MCOLN3	ENSCJAP00000012690	ENSCJAP00000012762	Mucolipin 2.	Mucolipin-3; Nonselective ligand-gated cation channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation channel with inwardly rectifying activity (By similarity). Mediates release of Ca(2+) from endosomes to the cytoplasm, contributes to endosomal acidification and is involved in the regulation of membrane trafficking and fusion in the endosomal pathway (By similarity). Does not seem to act as mechanosensory transduction channel in inner ear sensory hair cells. Proposed to play a critical role at the cochlear stereocilia ankle-lin [...]	0.980
MCOLN2	P2RY6	ENSCJAP00000012690	ENSCJAP00000040755	Mucolipin 2.	Pyrimidinergic receptor P2Y6.	0.568
MCOLN2	PDF	ENSCJAP00000012690	ENSCJAP00000028313	Mucolipin 2.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.	0.583