STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCOLN2Mucolipin 2. (574 aa)    
Predicted Functional Partners:
MCOLN3
Mucolipin-3; Nonselective ligand-gated cation channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation channel with inwardly rectifying activity (By similarity). Mediates release of Ca(2+) from endosomes to the cytoplasm, contributes to endosomal acidification and is involved in the regulation of membrane trafficking and fusion in the endosomal pathway (By similarity). Does not seem to act as mechanosensory transduction channel in inner ear sensory hair cells. Proposed to play a critical role at the cochlear stereocilia ankle-lin [...]
  
 
0.951
MCOLN1
Mucolipin 1.
  
 
0.946
TRPA1
Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.
     
 0.516
ENSCJAP00000074997
LSDAT_euk domain-containing protein.
     
 0.513
ADAR
Adenosine deaminase RNA specific.
      
 0.501
P2RY6
Pyrimidinergic receptor P2Y6.
      
 0.499
API5
Uncharacterized protein.
    
 
 0.489
VSIG10
V-set and immunoglobulin domain containing 10.
    
 
 0.478
SART1
Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.
      
 0.432
ISG20L2
Interferon stimulated exonuclease gene 20 like 2.
   
  
 0.432
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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