Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CUL4ACullin 4A; Belongs to the cullin family. (763 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 0.999
CUL4B
Cullin 4B; Belongs to the cullin family.
  
0.999
VPRBP
DDB1 and CUL4 associated factor 1.
   
 0.998
DDB2
Damage specific DNA binding protein 2.
    
 0.991
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.988
DTL
WD_REPEATS_REGION domain-containing protein.
    
 0.988
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.983
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
 0.980
WDTC1
WD and tetratricopeptide repeats protein 1 isoform a.
    
 0.976
COPS2
COP9 signalosome complex subunit 2 isoform 2.
   
 0.973
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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