IGDCC4 protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IGDCC4

Immunoglobulin superfamily DCC subclass member 4. (1248 aa)

Predicted Functional Partners:

APPL1

0.924

APPL2

0.924

NTN5

0.798

NTN3

0.798

NTN1

0.798

NTNG1

0.701

DRAXIN

0.695

NTNG2

0.693

TRIM9

0.668

NTN4

0.666

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL1	APPL2	ENSCJAP00000020399	ENSCJAP00000027523	DCC-interacting protein 13-alpha.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.989
APPL1	IGDCC4	ENSCJAP00000020399	ENSCJAP00000012906	DCC-interacting protein 13-alpha.	Immunoglobulin superfamily DCC subclass member 4.	0.924
APPL2	APPL1	ENSCJAP00000027523	ENSCJAP00000020399	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	DCC-interacting protein 13-alpha.	0.989
APPL2	IGDCC4	ENSCJAP00000027523	ENSCJAP00000012906	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Immunoglobulin superfamily DCC subclass member 4.	0.924
DRAXIN	IGDCC4	ENSCJAP00000024425	ENSCJAP00000012906	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Immunoglobulin superfamily DCC subclass member 4.	0.695
DRAXIN	NTN1	ENSCJAP00000024425	ENSCJAP00000060842	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin-1.	0.905
DRAXIN	NTN3	ENSCJAP00000024425	ENSCJAP00000027475	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin 3.	0.700
DRAXIN	NTN5	ENSCJAP00000024425	ENSCJAP00000000565	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin 5.	0.627
DRAXIN	NTNG1	ENSCJAP00000024425	ENSCJAP00000016137	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin G1.	0.585
DRAXIN	NTNG2	ENSCJAP00000024425	ENSCJAP00000075913	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin G2.	0.524
IGDCC4	APPL1	ENSCJAP00000012906	ENSCJAP00000020399	Immunoglobulin superfamily DCC subclass member 4.	DCC-interacting protein 13-alpha.	0.924
IGDCC4	APPL2	ENSCJAP00000012906	ENSCJAP00000027523	Immunoglobulin superfamily DCC subclass member 4.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.924
IGDCC4	DRAXIN	ENSCJAP00000012906	ENSCJAP00000024425	Immunoglobulin superfamily DCC subclass member 4.	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	0.695
IGDCC4	NTN1	ENSCJAP00000012906	ENSCJAP00000060842	Immunoglobulin superfamily DCC subclass member 4.	Netrin-1.	0.798
IGDCC4	NTN3	ENSCJAP00000012906	ENSCJAP00000027475	Immunoglobulin superfamily DCC subclass member 4.	Netrin 3.	0.798
IGDCC4	NTN4	ENSCJAP00000012906	ENSCJAP00000004944	Immunoglobulin superfamily DCC subclass member 4.	Netrin-4.	0.666
IGDCC4	NTN5	ENSCJAP00000012906	ENSCJAP00000000565	Immunoglobulin superfamily DCC subclass member 4.	Netrin 5.	0.798
IGDCC4	NTNG1	ENSCJAP00000012906	ENSCJAP00000016137	Immunoglobulin superfamily DCC subclass member 4.	Netrin G1.	0.701
IGDCC4	NTNG2	ENSCJAP00000012906	ENSCJAP00000075913	Immunoglobulin superfamily DCC subclass member 4.	Netrin G2.	0.693
IGDCC4	TRIM9	ENSCJAP00000012906	ENSCJAP00000055879	Immunoglobulin superfamily DCC subclass member 4.	Tripartite motif containing 9.	0.668