TLE3 protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TLE3

TLE family member 3, transcriptional corepressor. (829 aa)

Predicted Functional Partners:

TLE1

0.988

TLE4

0.974

RBPJ

0.931

HDAC1

0.921

RBPJL

0.919

HDAC2

0.899

XIAP

0.895

TLE2

0.892

ENSCJAP00000068726

0.892

ENSCJAP00000069660

0.892

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCJAP00000068726	HDAC1	ENSCJAP00000068726	ENSCJAP00000079075	TLE_N domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.519
ENSCJAP00000068726	HDAC2	ENSCJAP00000068726	ENSCJAP00000074750	TLE_N domain-containing protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.519
ENSCJAP00000068726	TLE1	ENSCJAP00000068726	ENSCJAP00000063157	TLE_N domain-containing protein.	TLE family member 1, transcriptional corepressor.	0.961
ENSCJAP00000068726	TLE3	ENSCJAP00000068726	ENSCJAP00000012910	TLE_N domain-containing protein.	TLE family member 3, transcriptional corepressor.	0.892
ENSCJAP00000068726	TLE4	ENSCJAP00000068726	ENSCJAP00000006133	TLE_N domain-containing protein.	TLE family member 4, transcriptional corepressor.	0.944
ENSCJAP00000068726	XIAP	ENSCJAP00000068726	ENSCJAP00000038195	TLE_N domain-containing protein.	Baculoviral IAP repeat-containing 4 (Predicted).	0.651
ENSCJAP00000069660	HDAC1	ENSCJAP00000069660	ENSCJAP00000079075	annotation not available	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.519
ENSCJAP00000069660	HDAC2	ENSCJAP00000069660	ENSCJAP00000074750	annotation not available	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.519
ENSCJAP00000069660	TLE1	ENSCJAP00000069660	ENSCJAP00000063157	annotation not available	TLE family member 1, transcriptional corepressor.	0.961
ENSCJAP00000069660	TLE3	ENSCJAP00000069660	ENSCJAP00000012910	annotation not available	TLE family member 3, transcriptional corepressor.	0.892
ENSCJAP00000069660	TLE4	ENSCJAP00000069660	ENSCJAP00000006133	annotation not available	TLE family member 4, transcriptional corepressor.	0.944
ENSCJAP00000069660	XIAP	ENSCJAP00000069660	ENSCJAP00000038195	annotation not available	Baculoviral IAP repeat-containing 4 (Predicted).	0.651
HDAC1	ENSCJAP00000068726	ENSCJAP00000079075	ENSCJAP00000068726	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	TLE_N domain-containing protein.	0.519
HDAC1	ENSCJAP00000069660	ENSCJAP00000079075	ENSCJAP00000069660	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	annotation not available	0.519
HDAC1	HDAC2	ENSCJAP00000079075	ENSCJAP00000074750	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.999
HDAC1	RBPJ	ENSCJAP00000079075	ENSCJAP00000060076	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Recombination signal binding protein for immunoglobulin kappa J region.	0.958
HDAC1	RBPJL	ENSCJAP00000079075	ENSCJAP00000032317	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Recombination signal binding protein for immunoglobulin kappa J region like.	0.948
HDAC1	TLE1	ENSCJAP00000079075	ENSCJAP00000063157	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	TLE family member 1, transcriptional corepressor.	0.964
HDAC1	TLE2	ENSCJAP00000079075	ENSCJAP00000034741	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	TLE family member 2, transcriptional corepressor.	0.899
HDAC1	TLE3	ENSCJAP00000079075	ENSCJAP00000012910	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	TLE family member 3, transcriptional corepressor.	0.921