STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DPP8Dipeptidyl peptidase 8 isoform 3; Belongs to the peptidase S9B family. (898 aa)    
Predicted Functional Partners:
PREP
Prolyl endopeptidase.
   
  
 0.837
CARD8
Caspase recruitment domain family member 8.
    
 
 0.807
DPP7
Dipeptidyl peptidase 7.
      
 0.775
PREPL
Prolyl endopeptidase-like isoform 1.
   
  
 0.740
NLRP1
NLR family pyrin domain containing 1.
   
 
 0.736
DPP9
Dipeptidyl peptidase 9; Belongs to the peptidase S9B family.
    
 
 0.718
XPNPEP3
Putative Xaa-Pro aminopeptidase 3 isoform 1.
      
 0.679
IL18
Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.
      
 0.598
UBR2
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.591
DPEP1
Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
      
 0.575
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.