| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KCTD2 | SUMO1 | ENSCJAP00000026903 | ENSCJAP00000062736 | Potassium channel tetramerization domain containing 2. | Small ubiquitin-related modifier. | 0.810 |
| KCTD2 | TOP1 | ENSCJAP00000026903 | ENSCJAP00000033572 | Potassium channel tetramerization domain containing 2. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.787 |
| KCTD2 | TOPORS | ENSCJAP00000026903 | ENSCJAP00000014529 | Potassium channel tetramerization domain containing 2. | E3 ubiquitin-protein ligase Topors isoform 1. | 0.608 |
| KLHL7 | TOPORS | ENSCJAP00000048813 | ENSCJAP00000014529 | Kelch-like protein 7 isoform 1. | E3 ubiquitin-protein ligase Topors isoform 1. | 0.704 |
| KLHL7 | USP45 | ENSCJAP00000048813 | ENSCJAP00000002435 | Kelch-like protein 7 isoform 1. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.760 |
| PCM1 | TOPORS | ENSCJAP00000025964 | ENSCJAP00000014529 | Pericentriolar material 1. | E3 ubiquitin-protein ligase Topors isoform 1. | 0.620 |
| PHACTR2 | TBL2 | ENSCJAP00000056426 | ENSCJAP00000031022 | Phosphatase and actin regulator. | Transducin beta-like protein 2. | 0.804 |
| PHACTR2 | TOPORS | ENSCJAP00000056426 | ENSCJAP00000014529 | Phosphatase and actin regulator. | E3 ubiquitin-protein ligase Topors isoform 1. | 0.688 |
| RP9 | TOPORS | ENSCJAP00000043815 | ENSCJAP00000014529 | Retinitis pigmentosa 9 protein. | E3 ubiquitin-protein ligase Topors isoform 1. | 0.592 |
| SUMO1 | KCTD2 | ENSCJAP00000062736 | ENSCJAP00000026903 | Small ubiquitin-related modifier. | Potassium channel tetramerization domain containing 2. | 0.810 |
| SUMO1 | TOP1 | ENSCJAP00000062736 | ENSCJAP00000033572 | Small ubiquitin-related modifier. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.654 |
| SUMO1 | TOPORS | ENSCJAP00000062736 | ENSCJAP00000014529 | Small ubiquitin-related modifier. | E3 ubiquitin-protein ligase Topors isoform 1. | 0.591 |
| SUMO1 | UBE2I | ENSCJAP00000062736 | ENSCJAP00000062635 | Small ubiquitin-related modifier. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.987 |
| TBL2 | PHACTR2 | ENSCJAP00000031022 | ENSCJAP00000056426 | Transducin beta-like protein 2. | Phosphatase and actin regulator. | 0.804 |
| TBL2 | TOPORS | ENSCJAP00000031022 | ENSCJAP00000014529 | Transducin beta-like protein 2. | E3 ubiquitin-protein ligase Topors isoform 1. | 0.684 |
| TOP1 | KCTD2 | ENSCJAP00000033572 | ENSCJAP00000026903 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Potassium channel tetramerization domain containing 2. | 0.787 |
| TOP1 | SUMO1 | ENSCJAP00000033572 | ENSCJAP00000062736 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Small ubiquitin-related modifier. | 0.654 |
| TOP1 | TOPORS | ENSCJAP00000033572 | ENSCJAP00000014529 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | E3 ubiquitin-protein ligase Topors isoform 1. | 0.621 |
| TOP1 | UBE2I | ENSCJAP00000033572 | ENSCJAP00000062635 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.787 |
| TOPORS | KCTD2 | ENSCJAP00000014529 | ENSCJAP00000026903 | E3 ubiquitin-protein ligase Topors isoform 1. | Potassium channel tetramerization domain containing 2. | 0.608 |