| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IL12RB1 | IL12RB2 | ENSCJAP00000056981 | ENSCJAP00000053990 | Interleukin 12 receptor subunit beta 1. | Interleukin 12 receptor subunit beta 2. | 0.829 |
| IL12RB1 | IL18R1 | ENSCJAP00000056981 | ENSCJAP00000015317 | Interleukin 12 receptor subunit beta 1. | Interleukin-18 receptor 1. | 0.547 |
| IL12RB2 | IL12RB1 | ENSCJAP00000053990 | ENSCJAP00000056981 | Interleukin 12 receptor subunit beta 2. | Interleukin 12 receptor subunit beta 1. | 0.829 |
| IL12RB2 | IL18R1 | ENSCJAP00000053990 | ENSCJAP00000015317 | Interleukin 12 receptor subunit beta 2. | Interleukin-18 receptor 1. | 0.579 |
| IL18 | IL18BP | ENSCJAP00000022914 | ENSCJAP00000028218 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | Interleukin-18-binding protein isoform c. | 0.909 |
| IL18 | IL18R1 | ENSCJAP00000022914 | ENSCJAP00000015317 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | Interleukin-18 receptor 1. | 0.996 |
| IL18 | IL18RAP | ENSCJAP00000022914 | ENSCJAP00000051512 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | Interleukin 18 receptor accessory protein. | 0.994 |
| IL18 | IL1R1 | ENSCJAP00000022914 | ENSCJAP00000067404 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | Interleukin-1 receptor type 1. | 0.571 |
| IL18 | IL33 | ENSCJAP00000022914 | ENSCJAP00000062500 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | Interleukin 33. | 0.741 |
| IL18 | IL37 | ENSCJAP00000022914 | ENSCJAP00000031896 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | Interleukin 37. | 0.539 |
| IL18BP | IL18 | ENSCJAP00000028218 | ENSCJAP00000022914 | Interleukin-18-binding protein isoform c. | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | 0.909 |
| IL18BP | IL18R1 | ENSCJAP00000028218 | ENSCJAP00000015317 | Interleukin-18-binding protein isoform c. | Interleukin-18 receptor 1. | 0.644 |
| IL18BP | IL18RAP | ENSCJAP00000028218 | ENSCJAP00000051512 | Interleukin-18-binding protein isoform c. | Interleukin 18 receptor accessory protein. | 0.470 |
| IL18BP | IL37 | ENSCJAP00000028218 | ENSCJAP00000031896 | Interleukin-18-binding protein isoform c. | Interleukin 37. | 0.831 |
| IL18R1 | IL12RB1 | ENSCJAP00000015317 | ENSCJAP00000056981 | Interleukin-18 receptor 1. | Interleukin 12 receptor subunit beta 1. | 0.547 |
| IL18R1 | IL12RB2 | ENSCJAP00000015317 | ENSCJAP00000053990 | Interleukin-18 receptor 1. | Interleukin 12 receptor subunit beta 2. | 0.579 |
| IL18R1 | IL18 | ENSCJAP00000015317 | ENSCJAP00000022914 | Interleukin-18 receptor 1. | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | 0.996 |
| IL18R1 | IL18BP | ENSCJAP00000015317 | ENSCJAP00000028218 | Interleukin-18 receptor 1. | Interleukin-18-binding protein isoform c. | 0.644 |
| IL18R1 | IL18RAP | ENSCJAP00000015317 | ENSCJAP00000051512 | Interleukin-18 receptor 1. | Interleukin 18 receptor accessory protein. | 0.996 |
| IL18R1 | IL1R1 | ENSCJAP00000015317 | ENSCJAP00000067404 | Interleukin-18 receptor 1. | Interleukin-1 receptor type 1. | 0.549 |