IL1RL2 protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

IL1RL2

Interleukin 1 receptor like 2. (620 aa)

Predicted Functional Partners:

IL1F10

0.993

IL36RN

0.984

IL1RAP

0.982

IL36A

0.972

IL36G

0.969

IL1A

0.910

MYD88

0.904

IL1B

0.903

IRAK1

0.879

TRAF6

0.859

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL1A	IL1B	ENSCJAP00000030146	ENSCJAP00000030094	Interleukin-1; Belongs to the IL-1 family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.999
IL1A	IL1F10	ENSCJAP00000030146	ENSCJAP00000059586	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.441
IL1A	IL1RAP	ENSCJAP00000030146	ENSCJAP00000026132	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1 receptor accessory protein isoform 3.	0.972
IL1A	IL1RL2	ENSCJAP00000030146	ENSCJAP00000015367	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor like 2.	0.910
IL1A	IL36A	ENSCJAP00000030146	ENSCJAP00000067615	Interleukin-1; Belongs to the IL-1 family.	Interleukin 36 alpha.	0.591
IL1A	IL36G	ENSCJAP00000030146	ENSCJAP00000073872	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.484
IL1A	IL36RN	ENSCJAP00000030146	ENSCJAP00000025597	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.629
IL1A	IRAK1	ENSCJAP00000030146	ENSCJAP00000026603	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1 receptor-associated kinase 1 isoform 1 (Predicted).	0.761
IL1A	MYD88	ENSCJAP00000030146	ENSCJAP00000018784	Interleukin-1; Belongs to the IL-1 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.799
IL1A	TRAF6	ENSCJAP00000030146	ENSCJAP00000020431	Interleukin-1; Belongs to the IL-1 family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.753
IL1B	IL1A	ENSCJAP00000030094	ENSCJAP00000030146	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1; Belongs to the IL-1 family.	0.999
IL1B	IL1F10	ENSCJAP00000030094	ENSCJAP00000059586	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1.	0.565
IL1B	IL1RAP	ENSCJAP00000030094	ENSCJAP00000026132	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1 receptor accessory protein isoform 3.	0.995
IL1B	IL1RL2	ENSCJAP00000030094	ENSCJAP00000015367	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 1 receptor like 2.	0.903
IL1B	IL36A	ENSCJAP00000030094	ENSCJAP00000067615	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 36 alpha.	0.492
IL1B	IL36G	ENSCJAP00000030094	ENSCJAP00000073872	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1.	0.507
IL1B	IL36RN	ENSCJAP00000030094	ENSCJAP00000025597	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1.	0.543
IL1B	IRAK1	ENSCJAP00000030094	ENSCJAP00000026603	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1 receptor-associated kinase 1 isoform 1 (Predicted).	0.821
IL1B	MYD88	ENSCJAP00000030094	ENSCJAP00000018784	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.881
IL1B	TRAF6	ENSCJAP00000030094	ENSCJAP00000020431	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.806