STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTX4E3 ubiquitin-protein ligase DTX4. (619 aa)    
Predicted Functional Partners:
NLRP4
NLR family pyrin domain containing 4.
    
 0.939
NOTCH4
Notch receptor 4.
     
 0.903
NOTCH2
Notch receptor 2.
     
 0.903
NOTCH3
Notch receptor 3.
     
 0.901
RNF7
Uncharacterized protein.
      
 0.780
RNF7-2
RING-type domain-containing protein.
      
 0.701
RNF19A
RBR-type E3 ubiquitin transferase.
      
 0.620
NLRP11
NLR family pyrin domain containing 11.
      
 0.620
TRIM38
Tripartite motif-containing protein 38.
    
 0.518
UBE2O
Ubiquitin-conjugating enzyme E2 O.
      
 0.499
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.