STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (775 aa)    
Predicted Functional Partners:
HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1.
  
 
0.939
TPCN1
Two pore segment channel 1.
   
 
 0.782
KCNN3
Potassium calcium-activated channel subfamily N member 3.
   
  
 0.655
CACNA1H
Calcium voltage-gated channel subunit alpha1 H.
   
 
 0.585
ENSCJAP00000067350
Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.
     
 0.581
NSF
N-ethylmaleimide sensitive factor, vesicle fusing ATPase.
      
 0.555
SCN2B
Sodium voltage-gated channel beta subunit 2.
   
  
 0.544
CACNA1D
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 
 0.542
CAV3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
    
 
 0.516
ANO1
Anoctamin.
      
 0.515
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.