STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (390 aa)    
Predicted Functional Partners:
PTK2B
Protein-tyrosine kinase 2-beta isoform a; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.934
PARVA
Parvin alpha.
   
 0.914
VCL
Vinculin.
   
 0.909
CCNJL
Cyclin J like; Belongs to the cyclin family.
    
 
 0.900
C1QTNF2
C1q and TNF related 2.
      
 0.900
PTPN12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
   
 0.842
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.841
GIT1
ARF GTPase-activating protein GIT1 isoform 1.
    
 
 0.835
PARVB
Parvin beta.
   
 0.833
TMEM217
Uncharacterized protein.
      
 0.819
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.