STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAPPA2Pappalysin 2. (1786 aa)    
Predicted Functional Partners:
IGFBP5
Insulin like growth factor binding protein 5.
    
 0.743
KCNJ16
Potassium voltage-gated channel subfamily J member 16.
      
 0.701
STC2
Stanniocalcin-2.
    
 
 0.609
PRG2
C-type lectin domain-containing protein.
    
 0.572
PRG3
Proteoglycan 3, pro eosinophil major basic protein 2.
    
 0.572
ADAM12
ADAM metallopeptidase domain 12.
      
 0.566
KIFAP3
Kinesin associated protein 3.
      
 0.564
TSHR
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
    
 
 0.512
IGF1
Insulin like growth factor 1.
     
 0.501
IGF2
Insulin like growth factor 2.
   
 0.492
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.