STAM protein (Callithrix jacchus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

STAM

Signal transducing adapter molecule 1. (539 aa)

Predicted Functional Partners:

HGS

0.992

STAM2

0.985

STAMBP

0.970

TSG101

0.955

JAK2

0.943

TYK2

0.933

JAK1

0.931

ITSN2

0.929

ENSCJAP00000078263

0.929

ENSCJAP00000059313

0.896

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCJAP00000059313	ENSCJAP00000078263	ENSCJAP00000059313	ENSCJAP00000078263	Uncharacterized protein.	Uncharacterized protein.	0.573
ENSCJAP00000059313	HGS	ENSCJAP00000059313	ENSCJAP00000002931	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.913
ENSCJAP00000059313	ITSN2	ENSCJAP00000059313	ENSCJAP00000014479	Uncharacterized protein.	Intersectin 2.	0.573
ENSCJAP00000059313	JAK1	ENSCJAP00000059313	ENSCJAP00000030953	Uncharacterized protein.	Tyrosine-protein kinase.	0.403
ENSCJAP00000059313	JAK2	ENSCJAP00000059313	ENSCJAP00000045402	Uncharacterized protein.	Tyrosine-protein kinase.	0.403
ENSCJAP00000059313	STAM	ENSCJAP00000059313	ENSCJAP00000015931	Uncharacterized protein.	Signal transducing adapter molecule 1.	0.896
ENSCJAP00000059313	STAM2	ENSCJAP00000059313	ENSCJAP00000055155	Uncharacterized protein.	Signal transducing adapter molecule 2.	0.896
ENSCJAP00000059313	STAMBP	ENSCJAP00000059313	ENSCJAP00000033060	Uncharacterized protein.	STAM-binding protein.	0.823
ENSCJAP00000059313	TSG101	ENSCJAP00000059313	ENSCJAP00000056503	Uncharacterized protein.	Uncharacterized protein.	0.786
ENSCJAP00000059313	TYK2	ENSCJAP00000059313	ENSCJAP00000012623	Uncharacterized protein.	Tyrosine-protein kinase.	0.403
ENSCJAP00000078263	ENSCJAP00000059313	ENSCJAP00000078263	ENSCJAP00000059313	Uncharacterized protein.	Uncharacterized protein.	0.573
ENSCJAP00000078263	HGS	ENSCJAP00000078263	ENSCJAP00000002931	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.931
ENSCJAP00000078263	ITSN2	ENSCJAP00000078263	ENSCJAP00000014479	Uncharacterized protein.	Intersectin 2.	0.945
ENSCJAP00000078263	JAK1	ENSCJAP00000078263	ENSCJAP00000030953	Uncharacterized protein.	Tyrosine-protein kinase.	0.473
ENSCJAP00000078263	JAK2	ENSCJAP00000078263	ENSCJAP00000045402	Uncharacterized protein.	Tyrosine-protein kinase.	0.473
ENSCJAP00000078263	STAM	ENSCJAP00000078263	ENSCJAP00000015931	Uncharacterized protein.	Signal transducing adapter molecule 1.	0.929
ENSCJAP00000078263	STAM2	ENSCJAP00000078263	ENSCJAP00000055155	Uncharacterized protein.	Signal transducing adapter molecule 2.	0.929
ENSCJAP00000078263	TYK2	ENSCJAP00000078263	ENSCJAP00000012623	Uncharacterized protein.	Tyrosine-protein kinase.	0.473
HGS	ENSCJAP00000059313	ENSCJAP00000002931	ENSCJAP00000059313	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Uncharacterized protein.	0.913
HGS	ENSCJAP00000078263	ENSCJAP00000002931	ENSCJAP00000078263	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Uncharacterized protein.	0.931