STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPING1Serpin family G member 1; Belongs to the serpin family. (534 aa)    
Predicted Functional Partners:
C1S
Complement C1s subcomponent; Belongs to the peptidase S1 family.
   
 0.999
C1R
Complement C1r; Belongs to the peptidase S1 family.
   
 0.997
MASP2
Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
   
 0.988
C1QB
Complement C1q B chain.
   
 0.979
C1QA
Complement C1q subcomponent subunit A.
   
 0.974
C1QC
Complement C1q subcomponent subunit C.
   
 0.971
MBL2
Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
     
 0.956
LOC100395728
C-type lectin domain-containing protein.
     
 0.951
LOC100397554
C-type lectin domain-containing protein.
     
 0.951
KLKB1
Kallikrein B1; Belongs to the peptidase S1 family.
   
 0.861
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.