Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
GRB7Growth factor receptor bound protein 7. (554 aa)    
Predicted Functional Partners:
ERBB2
Receptor protein-tyrosine kinase.
 
 
 0.970
ERBB3
Receptor tyrosine-protein kinase erbB-3 isoform 1.
   
 0.846
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.827
LAX1
Lymphocyte transmembrane adaptor 1.
    
   0.809
SHC1
SHC-transforming protein 1 isoform 3.
    
 0.787
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.768
RND1
Rho-related GTP-binding protein Rho6.
    
 0.758
TEK
TEK receptor tyrosine kinase.
    
 0.745
ERBB4
Receptor protein-tyrosine kinase.
   
 0.730
FOXA2
Forkhead box A2.
      
 0.717
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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