EEF2K protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EEF2K

Eukaryotic elongation factor 2 kinase. (723 aa)

Predicted Functional Partners:

EEF2

0.994

PRKAB1

0.949

RPS6KB1

0.948

PRKAA1

0.916

PRKAA2

0.916

PRKCA

0.915

PRKCG

0.915

PRKCB

0.915

PRKAG2

0.909

PRKAG3

0.909

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF2	EEF2K	ENSCJAP00000045718	ENSCJAP00000016581	Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]	Eukaryotic elongation factor 2 kinase.	0.994
EEF2	PRKAB1	ENSCJAP00000045718	ENSCJAP00000048298	Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]	Protein kinase AMP-activated non-catalytic subunit beta 1.	0.436
EEF2	RPS6KB1	ENSCJAP00000045718	ENSCJAP00000048517	Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.410
EEF2K	EEF2	ENSCJAP00000016581	ENSCJAP00000045718	Eukaryotic elongation factor 2 kinase.	Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]	0.994
EEF2K	PRKAA1	ENSCJAP00000016581	ENSCJAP00000013705	Eukaryotic elongation factor 2 kinase.	Non-specific serine/threonine protein kinase.	0.916
EEF2K	PRKAA2	ENSCJAP00000016581	ENSCJAP00000029269	Eukaryotic elongation factor 2 kinase.	Non-specific serine/threonine protein kinase.	0.916
EEF2K	PRKAB1	ENSCJAP00000016581	ENSCJAP00000048298	Eukaryotic elongation factor 2 kinase.	Protein kinase AMP-activated non-catalytic subunit beta 1.	0.949
EEF2K	PRKAG2	ENSCJAP00000016581	ENSCJAP00000037977	Eukaryotic elongation factor 2 kinase.	Protein kinase AMP-activated non-catalytic subunit gamma 2.	0.909
EEF2K	PRKAG3	ENSCJAP00000016581	ENSCJAP00000073045	Eukaryotic elongation factor 2 kinase.	Protein kinase AMP-activated non-catalytic subunit gamma 3.	0.909
EEF2K	PRKCA	ENSCJAP00000016581	ENSCJAP00000000588	Eukaryotic elongation factor 2 kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.915
EEF2K	PRKCB	ENSCJAP00000016581	ENSCJAP00000069922	Eukaryotic elongation factor 2 kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.915
EEF2K	PRKCG	ENSCJAP00000016581	ENSCJAP00000051209	Eukaryotic elongation factor 2 kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.915
EEF2K	RPS6KB1	ENSCJAP00000016581	ENSCJAP00000048517	Eukaryotic elongation factor 2 kinase.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.948
PRKAA1	EEF2K	ENSCJAP00000013705	ENSCJAP00000016581	Non-specific serine/threonine protein kinase.	Eukaryotic elongation factor 2 kinase.	0.916
PRKAA1	PRKAA2	ENSCJAP00000013705	ENSCJAP00000029269	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.994
PRKAA1	PRKAB1	ENSCJAP00000013705	ENSCJAP00000048298	Non-specific serine/threonine protein kinase.	Protein kinase AMP-activated non-catalytic subunit beta 1.	0.998
PRKAA1	PRKAG2	ENSCJAP00000013705	ENSCJAP00000037977	Non-specific serine/threonine protein kinase.	Protein kinase AMP-activated non-catalytic subunit gamma 2.	0.997
PRKAA1	PRKAG3	ENSCJAP00000013705	ENSCJAP00000073045	Non-specific serine/threonine protein kinase.	Protein kinase AMP-activated non-catalytic subunit gamma 3.	0.995
PRKAA2	EEF2K	ENSCJAP00000029269	ENSCJAP00000016581	Non-specific serine/threonine protein kinase.	Eukaryotic elongation factor 2 kinase.	0.916
PRKAA2	PRKAA1	ENSCJAP00000029269	ENSCJAP00000013705	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.994