STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHD7Chromodomain-helicase-DNA-binding protein 7. (2994 aa)    
Predicted Functional Partners:
INO80C
INO80 complex subunit C isoform 2.
    
 0.720
CPA6
Carboxypeptidase A6.
    
 
 0.691
CTNNB1
Catenin beta 1.
    
 0.689
POLR2C
RNA polymerase II subunit C.
   
 0.643
CHD8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]
  
 
 
0.640
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 
 0.637
ARID4B
AT-rich interaction domain 4B.
   
 0.633
FANCM
FA complementation group M.
    
 0.628
ARID4A
AT-rich interactive domain-containing protein 4A isoform I.
   
 0.625
SUPT5H
Transcription elongation factor SPT5.
   
 
 0.621
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.