STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHC1SHC-transforming protein 1 isoform 3. (577 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2 isoform 1.
   
 0.999
EGFR
Receptor protein-tyrosine kinase.
    
 0.998
ERBB2
Receptor protein-tyrosine kinase.
    
 0.995
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.995
NTRK1
Tyrosine-protein kinase receptor.
   
 0.995
ERBB3
Receptor tyrosine-protein kinase erbB-3 isoform 1.
    
 0.993
SRC
Tyrosine-protein kinase.
   
0.993
IGF1R
Tyrosine-protein kinase receptor.
    
 0.992
ERBB4
Receptor protein-tyrosine kinase.
    
 0.989
GAB1
GRB2 associated binding protein 1.
    
 0.987
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.