STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIVA1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)    
Predicted Functional Partners:
BCL2L1
Bcl-2-like protein 1 isoform 1.
    
 0.953
CASP6
Caspase 6; Belongs to the peptidase C14A family.
      
 0.706
CD27
CD27 molecule.
    
 
 0.645
MRPL16
39S ribosomal protein L16, mitochondrial; Belongs to the universal ribosomal protein uL16 family.
   
  
 0.625
FZR1
Fizzy and cell division cycle 20 related 1.
   
  
 0.624
TMEM62
Transmembrane protein 62.
      
 0.620
MAN1A1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
      
 0.620
CDHR2
Cadherin related family member 2.
      
 0.617
CWC15
CWC15 spliceosome associated protein homolog.
      
 0.612
BOP1
Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
      
 0.611
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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