RAD9B protein (Callithrix jacchus) - STRING interaction network

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RAD9B

Cell cycle checkpoint control protein; Belongs to the rad9 family. (428 aa)

Predicted Functional Partners:

RAD1

0.994

HUS1

0.989

ATR

0.983

RAD9A

0.945

TOPBP1

0.930

RAD17

0.922

WRN

0.898

RFC4

0.898

RFC2

0.892

ATM

0.892

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	ATR	ENSCJAP00000018844	ENSCJAP00000003355	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.995
ATM	HUS1	ENSCJAP00000018844	ENSCJAP00000027130	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Checkpoint protein; Belongs to the HUS1 family.	0.885
ATM	RAD1	ENSCJAP00000018844	ENSCJAP00000060991	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	RAD1 checkpoint DNA exonuclease.	0.933
ATM	RAD17	ENSCJAP00000018844	ENSCJAP00000029828	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell cycle checkpoint protein RAD17 isoform 2.	0.962
ATM	RAD9A	ENSCJAP00000018844	ENSCJAP00000001792	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.923
ATM	RAD9B	ENSCJAP00000018844	ENSCJAP00000017066	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.892
ATM	RFC2	ENSCJAP00000018844	ENSCJAP00000007251	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Replication factor C subunit 2.	0.863
ATM	RFC4	ENSCJAP00000018844	ENSCJAP00000067625	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Replication factor C subunit 4.	0.871
ATM	TOPBP1	ENSCJAP00000018844	ENSCJAP00000077630	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	DNA topoisomerase II binding protein 1.	0.967
ATM	WRN	ENSCJAP00000018844	ENSCJAP00000022986	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	WRN RecQ like helicase.	0.981
ATR	ATM	ENSCJAP00000003355	ENSCJAP00000018844	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.995
ATR	HUS1	ENSCJAP00000003355	ENSCJAP00000027130	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Checkpoint protein; Belongs to the HUS1 family.	0.992
ATR	RAD1	ENSCJAP00000003355	ENSCJAP00000060991	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RAD1 checkpoint DNA exonuclease.	0.990
ATR	RAD17	ENSCJAP00000003355	ENSCJAP00000029828	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint protein RAD17 isoform 2.	0.976
ATR	RAD9A	ENSCJAP00000003355	ENSCJAP00000001792	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.993
ATR	RAD9B	ENSCJAP00000003355	ENSCJAP00000017066	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.983
ATR	RFC2	ENSCJAP00000003355	ENSCJAP00000007251	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Replication factor C subunit 2.	0.841
ATR	RFC4	ENSCJAP00000003355	ENSCJAP00000067625	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Replication factor C subunit 4.	0.858
ATR	TOPBP1	ENSCJAP00000003355	ENSCJAP00000077630	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	DNA topoisomerase II binding protein 1.	0.980
ATR	WRN	ENSCJAP00000003355	ENSCJAP00000022986	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	WRN RecQ like helicase.	0.970