FAM107B protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FAM107B

Family with sequence similarity 107 member B. (306 aa)

Predicted Functional Partners:

OSTN

0.716

NOVA2

0.578

NOVA1

0.572

NEO1

0.551

ENSCJAP00000068253

0.538

PCNP

0.538

ARHGEF3

0.512

LHFPL2

0.492

MST1R

0.470

MET

0.470

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF3	FAM107B	ENSCJAP00000072928	ENSCJAP00000017203	Rho guanine nucleotide exchange factor 3.	Family with sequence similarity 107 member B.	0.512
ARHGEF3	LHFPL2	ENSCJAP00000072928	ENSCJAP00000072991	Rho guanine nucleotide exchange factor 3.	Uncharacterized protein.	0.582
ENSCJAP00000068253	FAM107B	ENSCJAP00000068253	ENSCJAP00000017203	Uncharacterized protein.	Family with sequence similarity 107 member B.	0.538
ENSCJAP00000068253	OSTN	ENSCJAP00000068253	ENSCJAP00000078265	Uncharacterized protein.	Osteocrin.	0.598
FAM107B	ARHGEF3	ENSCJAP00000017203	ENSCJAP00000072928	Family with sequence similarity 107 member B.	Rho guanine nucleotide exchange factor 3.	0.512
FAM107B	ENSCJAP00000068253	ENSCJAP00000017203	ENSCJAP00000068253	Family with sequence similarity 107 member B.	Uncharacterized protein.	0.538
FAM107B	LHFPL2	ENSCJAP00000017203	ENSCJAP00000072991	Family with sequence similarity 107 member B.	Uncharacterized protein.	0.492
FAM107B	MET	ENSCJAP00000017203	ENSCJAP00000009442	Family with sequence similarity 107 member B.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.470
FAM107B	MST1R	ENSCJAP00000017203	ENSCJAP00000008287	Family with sequence similarity 107 member B.	Macrophage stimulating 1 receptor.	0.470
FAM107B	NEO1	ENSCJAP00000017203	ENSCJAP00000033569	Family with sequence similarity 107 member B.	Neogenin isoform 1.	0.551
FAM107B	NOVA1	ENSCJAP00000017203	ENSCJAP00000011479	Family with sequence similarity 107 member B.	RNA-binding protein Nova-1 isoform 1.	0.572
FAM107B	NOVA2	ENSCJAP00000017203	ENSCJAP00000022266	Family with sequence similarity 107 member B.	NOVA alternative splicing regulator 2.	0.578
FAM107B	OSTN	ENSCJAP00000017203	ENSCJAP00000078265	Family with sequence similarity 107 member B.	Osteocrin.	0.716
FAM107B	PCNP	ENSCJAP00000017203	ENSCJAP00000071670	Family with sequence similarity 107 member B.	PEST proteolytic signal-containing nuclear protein.	0.538
LHFPL2	ARHGEF3	ENSCJAP00000072991	ENSCJAP00000072928	Uncharacterized protein.	Rho guanine nucleotide exchange factor 3.	0.582
LHFPL2	FAM107B	ENSCJAP00000072991	ENSCJAP00000017203	Uncharacterized protein.	Family with sequence similarity 107 member B.	0.492
MET	FAM107B	ENSCJAP00000009442	ENSCJAP00000017203	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Family with sequence similarity 107 member B.	0.470
MET	MST1R	ENSCJAP00000009442	ENSCJAP00000008287	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Macrophage stimulating 1 receptor.	0.694
MST1R	FAM107B	ENSCJAP00000008287	ENSCJAP00000017203	Macrophage stimulating 1 receptor.	Family with sequence similarity 107 member B.	0.470
MST1R	MET	ENSCJAP00000008287	ENSCJAP00000009442	Macrophage stimulating 1 receptor.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.694