Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBX5T-box transcription factor TBX5 isoform 1. (518 aa)    
Predicted Functional Partners:
NKX2-5
NK2 homeobox 5.
   
 0.984
GATA4
GATA binding protein 4.
   
 0.925
WWTR1
WW domain-containing protein.
    
 0.883
MEF2C
Myocyte-specific enhancer factor 2C isoform 3.
    
 
 0.869
HAND2
Heart and neural crest derivatives expressed 2.
    
 0.863
YAP1
Yes associated protein 1.
    
 0.854
KAT5
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
  0.841
GATA5
GATA binding protein 5.
   
 0.811
NPPA
Natriuretic peptide A.
    
 0.783
ISL1
Insulin gene enhancer protein ISL-1.
    
 0.769
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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