STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRRX1Paired related homeobox 1. (245 aa)    
Predicted Functional Partners:
ZNF366
Zinc finger protein 366.
   
 
 0.699
GLIS1
GLIS family zinc finger 1.
   
 
 0.636
ZNF789
Zinc finger protein 789.
   
 
 0.628
TWIST1
Twist-related protein 1; Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN w [...]
   
  
 0.567
HHEX
Hematopoietically-expressed homeobox protein HHEX.
      
0.565
TBX18
T-box transcription factor 18.
   
 
 0.545
KLF12
Kruppel like factor 12.
   
 
 0.529
COL1A1
Collagen alpha-1(I) chain preproprotein.
   
 
 0.518
CDC14A
Cell division cycle 14A.
    
 
 0.506
KLF8
Kruppel like factor 8.
   
 
 0.496
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.