STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LONRF2LON peptidase N-terminal domain and RING finger protein 2. (753 aa)    
Predicted Functional Partners:
CHST10
Carbohydrate sulfotransferase.
      
 0.816
ADAD1
Adenosine deaminase domain containing 1.
      
 0.772
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.623
PTPN2
Tyrosine-protein phosphatase non-receptor type.
      
 0.620
TRIP12
Uncharacterized protein.
    
 0.608
RPS26
40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.
      
 0.595
AFF3
AF4/FMR2 family member 3 isoform 2.
   
 0.581
SYPL2
Synaptophysin like 2.
      
 0.581
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
     
 0.549
UBC
Uncharacterized protein.
    
 0.525
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.