Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (990 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.888
ENSCJAP00000061225
Myocyte enhancer factor 2A.
   
 
 0.875
SIRT1
Sirtuin 1.
    
 0.867
EGFR
Receptor protein-tyrosine kinase.
    
 
 0.833
NCOR2
Nuclear receptor corepressor 2.
   
 0.821
H2AZ1
Histone H2A; Belongs to the histone H2A family.
   
 0.773
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
 0.773
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
   
 
 0.772
MACROH2A1
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
    
 0.748
MACROH2A2
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
    
 0.748
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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