SLF1 protein (Callithrix jacchus) - STRING interaction network

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Score

SLF1

Ankyrin repeat domain-containing protein 32. (1059 aa)

Predicted Functional Partners:

CDC45

0.993

BARD1

0.989

ATR

0.988

WRN

0.978

ATM

0.972

RAD1

0.965

RAD17

0.964

RHNO1

0.963

DNA2

0.959

ATRIP

0.958

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	ATR	ENSCJAP00000018844	ENSCJAP00000003355	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.999
ATM	ATRIP	ENSCJAP00000018844	ENSCJAP00000005270	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	ATR-interacting protein isoform 1.	0.901
ATM	BARD1	ENSCJAP00000018844	ENSCJAP00000021140	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	BRCA1 associated RING domain 1.	0.984
ATM	CDC45	ENSCJAP00000018844	ENSCJAP00000002789	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell division cycle 45.	0.519
ATM	DNA2	ENSCJAP00000018844	ENSCJAP00000035423	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	DNA replication helicase/nuclease 2.	0.925
ATM	RAD1	ENSCJAP00000018844	ENSCJAP00000060991	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	RAD1 checkpoint DNA exonuclease.	0.926
ATM	RAD17	ENSCJAP00000018844	ENSCJAP00000029828	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell cycle checkpoint protein RAD17 isoform 2.	0.958
ATM	RHNO1	ENSCJAP00000018844	ENSCJAP00000034914	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 isoform 1.	0.571
ATM	SLF1	ENSCJAP00000018844	ENSCJAP00000019184	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Ankyrin repeat domain-containing protein 32.	0.972
ATM	WRN	ENSCJAP00000018844	ENSCJAP00000022986	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	WRN RecQ like helicase.	0.990
ATR	ATM	ENSCJAP00000003355	ENSCJAP00000018844	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.999
ATR	ATRIP	ENSCJAP00000003355	ENSCJAP00000005270	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	ATR-interacting protein isoform 1.	0.999
ATR	BARD1	ENSCJAP00000003355	ENSCJAP00000021140	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	BRCA1 associated RING domain 1.	0.874
ATR	CDC45	ENSCJAP00000003355	ENSCJAP00000002789	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Cell division cycle 45.	0.878
ATR	DNA2	ENSCJAP00000003355	ENSCJAP00000035423	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	DNA replication helicase/nuclease 2.	0.861
ATR	RAD1	ENSCJAP00000003355	ENSCJAP00000060991	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RAD1 checkpoint DNA exonuclease.	0.990
ATR	RAD17	ENSCJAP00000003355	ENSCJAP00000029828	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint protein RAD17 isoform 2.	0.958
ATR	RHNO1	ENSCJAP00000003355	ENSCJAP00000034914	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 isoform 1.	0.615
ATR	SLF1	ENSCJAP00000003355	ENSCJAP00000019184	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Ankyrin repeat domain-containing protein 32.	0.988
ATR	WRN	ENSCJAP00000003355	ENSCJAP00000022986	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	WRN RecQ like helicase.	0.996