DGCR8 protein (Callithrix jacchus) - STRING interaction network

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Score

DGCR8

Microprocessor complex subunit DGCR8 isoform 1. (773 aa)

Predicted Functional Partners:

DROSHA

0.999

XPO5

0.975

DICER1

0.959

AGO2

0.912

TARBP2

0.878

MRPL44

0.826

AGO1

0.809

PRKRA

0.809

USP36

0.794

DDX5

0.788

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO1	AGO2	ENSCJAP00000003030	ENSCJAP00000056892	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.998
AGO1	DGCR8	ENSCJAP00000003030	ENSCJAP00000019940	Argonaute RISC component 1; Belongs to the argonaute family.	Microprocessor complex subunit DGCR8 isoform 1.	0.809
AGO1	DICER1	ENSCJAP00000003030	ENSCJAP00000051203	Argonaute RISC component 1; Belongs to the argonaute family.	Endoribonuclease Dicer isoform 1; Belongs to the helicase family. Dicer subfamily.	0.991
AGO1	DROSHA	ENSCJAP00000003030	ENSCJAP00000035201	Argonaute RISC component 1; Belongs to the argonaute family.	Ribonuclease 3 isoform 1.	0.921
AGO1	MRPL44	ENSCJAP00000003030	ENSCJAP00000070343	Argonaute RISC component 1; Belongs to the argonaute family.	Mitochondrial ribosomal protein L44.	0.700
AGO1	PRKRA	ENSCJAP00000003030	ENSCJAP00000040074	Argonaute RISC component 1; Belongs to the argonaute family.	Interferon-inducible double stranded RNA-dependent protein kinase activator A isoform 1.	0.899
AGO1	TARBP2	ENSCJAP00000003030	ENSCJAP00000034713	Argonaute RISC component 1; Belongs to the argonaute family.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.955
AGO1	XPO5	ENSCJAP00000003030	ENSCJAP00000045858	Argonaute RISC component 1; Belongs to the argonaute family.	Exportin 5.	0.851
AGO2	AGO1	ENSCJAP00000056892	ENSCJAP00000003030	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Argonaute RISC component 1; Belongs to the argonaute family.	0.998
AGO2	DDX5	ENSCJAP00000056892	ENSCJAP00000035916	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	0.460
AGO2	DGCR8	ENSCJAP00000056892	ENSCJAP00000019940	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Microprocessor complex subunit DGCR8 isoform 1.	0.912
AGO2	DICER1	ENSCJAP00000056892	ENSCJAP00000051203	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Endoribonuclease Dicer isoform 1; Belongs to the helicase family. Dicer subfamily.	0.997
AGO2	DROSHA	ENSCJAP00000056892	ENSCJAP00000035201	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Ribonuclease 3 isoform 1.	0.963
AGO2	MRPL44	ENSCJAP00000056892	ENSCJAP00000070343	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Mitochondrial ribosomal protein L44.	0.700
AGO2	PRKRA	ENSCJAP00000056892	ENSCJAP00000040074	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Interferon-inducible double stranded RNA-dependent protein kinase activator A isoform 1.	0.962
AGO2	TARBP2	ENSCJAP00000056892	ENSCJAP00000034713	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.992
AGO2	XPO5	ENSCJAP00000056892	ENSCJAP00000045858	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Exportin 5.	0.930
DDX5	AGO2	ENSCJAP00000035916	ENSCJAP00000056892	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.460
DDX5	DGCR8	ENSCJAP00000035916	ENSCJAP00000019940	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Microprocessor complex subunit DGCR8 isoform 1.	0.788
DDX5	DROSHA	ENSCJAP00000035916	ENSCJAP00000035201	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Ribonuclease 3 isoform 1.	0.988